| presynaptic terminals: from basic biology to dysregulation in brain disease | Medical Faculty Heidelberg | Institute of Anatomy and Cell Biology | |
| cellular neuroscience with a focus on glial cell physiology | Medical Faculty Heidelberg | Institute of Anatomy and Cell Biology | |
| activity of neurons in mice during exploratory behavior | Medical Faculty Heidelberg / DKFZ | Department of Clinical Neurobiology | |
| translational neuroscience | Heidelberg University Hospital | Institute of Human Genetics | |
| I am interested in the cerebral organization of somatosensory processing, and especially the functional reorganization occurring after peripheral changes (e.g. amputation) or after a “virtual” brain lesion such as Transcranial magnetic stimulation (TMS). In my previous research, I have been combining TMS and functional imaging (fMRI) to map the neural plasticity in sensory areas. This combination could be useful to optimize therapeutic application of TMS in sensory-related disorders. | Central Institute of Mental Health | Cognitive and Clinical Neuroscience | |
| evolution of the nervous system in bilateria | European Molecular Biology Laboratory | | |
| neuronal calcium signaling; synaptic activity-driven transcription, NMDA receptor functions in survival and cell death, neuroprotection, drug discovery | | Institute of Neurobiology | |
| magnetic resonance neurography | Heidelberg University Hospital | | |
| molecular neurogenetics, disease modelling, neurodevelopmental disorders, iPSC-derived neuronal stem cells and neurons | Heidelberg University Hospital | Institute of Human Genetics | |
| cell morphological correlates of cognitive functions | Medical Faculty Heidelberg | Institute of Physiology and Pathophysiology | |
| molecular and cellular imaging of neuroinflammation and the tumor microenvironment of glioma, translational imaging, immuno-imaging, high field MRI, optical imaging, light sheet microscopy | | University Hospital Heidelberg | |
| proliferation and differentiation of neural stem cells in the developing and aging brain and in response to neuronal activity | | Institute of Neurobiology | |
| neuroinflammation and neurodegeneration | Heidelberg University Hospital | | |
| impact of social relationships on health | Heidelberg University Hospital | Institute for Medical Psychology | |
| neuronal network oscillations, cellular electrophysiology, theory of neurosciences | Medical Faculty Heidelberg | Institute of Physiology and Pathophysiology | |
| | Central Institute of Mental Health | Department of Theoretical Neuroscience | |
| retinal degeneration, autoimmune disease, neuroinflammation, multiple sclerosis | Heidelberg University Hospital | | |
| | Central Institute of Mental Health | Neuropeptide Research in Psychiatry | |
| systems neuroscience, cortico-subcortical loops, learning, sensory processing, neurophysiology, optogenetics | Heidelberg University Hospital | Institute of Physiology and Pathophysiology | |
| pathophysiology and pathogenesis (risk & resilience) in major psychiatric disorders; neurofunctional connectivity magnetic resonance imaging | Heidelberg University Hospital | Center for Psychosocial Medicine | |
| auditory perception and cognition | Heidelberg University Hospital | | |
| immunobiology of brain tumors, drug screening, personalized medicine, tumor organoids and other patient-derived disease models | Heidelberg University Hospital | | |
| | Heidelberg University Hospital | Center for Psychosocial Medicine | |
| protein quality control and neurodegeneration | | Center for Molecular Biology | |
| cellular neurosciences, brain energy metabolism, neuroinflammation, neuronal oscillations, microglia, electrophysiology | Medical Faculty Heidelberg | Institute of Physiology and Pathophysiology | |
| social and reinforcement learning, cognition, complex social behavior, in vivo neurophysiology and imaging, computational modelling | Central Institute of Mental Health | Clinic for Phychiatry and Psychotherapy | |
| molecular cell biology of synapses | Medical Faculty Heidelberg | Institute for Anatomy and Cell Biology | |
| molecular and cellular mechanisms underlying learning, memory, and adaptive behaviors in mice, e.g. extinction of remote fear memory; neuromodulation of hippocampal-prefontal networks | | Department of Neurophysiology | |
| neuropaediatrics and metabolic medicine | Heidelberg University Hospital | Neuropediatics and Metabolic Medicine | |
| molecular mechanisms underlying chronic pain | Medical Faculty Heidelberg | Institute of Pharmacology | |
| | Medical Faculty Heidelberg | Institute for Anatomy and Cell Biology | |
| cerebellum development, pediatric brain cancer, functional genetics | German Cancer Research Center | Functional and Structural Genomics | |
| molecular neurogenetics, gliobastoma, metabolism, organoid, drug development | German Cancer Research Center | | |
| | German Cancer Research Center | Imaging and Radiooncology | |
| cell fate engineering, disease modeling, transcriptional networks, stem cell biology, cancer neuroscience | German Cancer Research Center | | |
| molecular and transcriptional control of neuronal morphology in health and disease | | Institute of Neurobiology | |
| psychiatry and psychotherapy | Central Institute of Mental Health | Clinic for Phychiatry and Psychotherapy | |
| | Heidelberg University Hospital | Department of Clinical Neurobiology | |
| We are studying neurodegenerative diseases and synaptic transmission disorders, in particular Alzheimers disease. To this end we use a combination of state of the art approaches including primary neuronal cultures, organotypic cultures and animal models. In this regard we have developped inducible KO and KI models of the amlyloid precursor protein APP and for the related APLPs. More recently we started to leverage the physiological functions of secreted neurotrophic APPs fragments for Alzheimer treatment. | | Institute of Pharmacy and Molecular Biotechnology | |
| molecular and cellular neurobiology, learning and memory | Central Institute of Mental Health | Molecular and Cellular Cognition Research | |
| neurodevelopment and related disorders, cancer neuroscience | | Institute of Neurobiology | |
| immune regulation in brain tumors, development of therapeutic strategies for the immunotherapy of gliomas and other types of cancer with a focus on adaptive immunity | Heidelberg University Hospital | | |
| neuro-imaging, multi-photon microscopy, systems neuroscience, cancer neuroscience | European Molecular Biology Laboratory | Cell Biology and Biophysics | |
| neuroregeneration, spinal cord injury, tissue engineering, neuroinflammation, central neuropathic pain, epigenetic regulation | Heidelberg University Hospital | Clinic for Paraplegiology | |
| neurodevelopment, glia-neuron interactions, glial biology, molecular neurogenetics, cell adhesion, nervous system aging, neurodegeneration | European Molecular Biology Laboratory | | |
| neuromuscular biology, neuromuscular model systems, organoids, microscopic 3D and live cell imaging, optical tissue clearing, AI-assisted 3D image analysis | | Mannheim Center for Translational Neuroscience | |
| | Heidelberg University Hospital | | |
| molecular genetics, neurodevelopmental disorders, iPSCs, mouse models | Heidelberg University Hospital | Institute of Human Genetics | |
| translational neurobiology, neuroimmunology | | Mannheim Center for Translational Neuroscience | |
| episodic memory, reward, addiction, entorhinal cortex | German Cancer Research Center | Department of Clinical Neurobiology | |
| experimental pain research | | Experimental Pain Research | |
| | | Institute of Neuroanatomy | |
| mechanisms of experience-dependent synaptic plasticity, learning and memory, and memory extinction | | Institute of Neurobiology | |
| reconstitution of neuronal exocytosis using purified components, biochemical and structural characterization to reveal molecular mechanisms | | Heidelberg University Biochemistry Center | |
| addiction neuroscience and comorbidities | Central Institute of Mental Health | Institute for Psychopharmacology | |
| congenital disorders of glycosylation | Heidelberg University Hospital | Congenital Disorders of Glycosylation | |
| mechanisms governing genome integrity in neural stem and progenitor cells, regulatory pathways influencing proliferative capacity during embryonic development | German Cancer Research Center | Functional and Structural Genomics | |
| | Heidelberg University Hospital | Clinic for Paraplegiology | |
| | | | |
| brain tumors, biomarkers, neuro-cancer interaction, immunotherapy | Heidelberg University Hospital | | |
| synaptic physiology, neuronal network dynamics, neuromodulatory systems, development of optogenetic tools and methods | | Mannheim Center for Translational Neuroscience | |
| mechanisms underlying the pathogenesis of multiple sclerosis (MS), neuromyelitis spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD) and other antibody-mediated autoimmune diseases, broadening diagnostic methods in the field of CSF analysis | Heidelberg University Hospital | | |
| developmental biology and physiology | | Center for Organismal Studies | |
